Effectiveness of Four Different Interventions Against Schistosoma haematobium in a Seasonal Transmission Setting of Cote d'Ivoire: A Cluster Randomized Trial.

ABSTRACT:

Background

Annual mass drug administration (MDA) using praziquantel is the cornerstone of schistosomiasis morbidity control but is not sufficient to interrupt transmission. We implemented a cluster-randomized trial to compare the effectiveness of 4 different intervention packages to interrupt transmission of Schistosoma haematobium in a seasonal transmission setting of Côte d'Ivoire.

Methods

Sixty-four localities with a S. haematobium prevalence in school children aged 13-14 years above 4% were randomly assigned to 1 of 4 intervention arms over a 3-year period: (1) the current standard strategy consisting of annual MDA before peak of transmission, (2) annual MDA after peak of transmission, (3) biannual MDA, and (4) standard MDA combined with snail control. The primary outcom

SUBMITTER: Ouattara M 

PROVIDER: S-EPMC9258925 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature