Dataset Information
First case of within-host co-infection of different SARS-CoV-2 variants in Ecuador.
Ontology highlight
ABSTRACT: Background
COVID-19 infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause mild symptoms to severe illness and death. Co-infections of SARS-CoV-2 with other respiratory viruses have been described. However, two SARS-CoV-2 lineage co-infection have been rarely reported.Methodology
A genotyping analysis and two different types of whole genome sequencing were performed (Illumina MiniSeq and ONT MinION). When examining the phylogenetic analysis in NextClade and Pangolin webservers, and considering the genotyping findings, conflicting results were obtained.Results
The raw data of the sequencing was analyzed, and nucleotide variants were identified between different reads of the virus genome. B.1 and P.1 lineages were identified within the same sample.Conclusions
We concluded that this is a co-infection case with two SARS-CoV-2 lineages, the first one reported in Ecuador.
SUBMITTER: Fernandez-Cadena JC
PROVIDER: S-EPMC9259011 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
Publications
First case of within-host co-infection of different SARS-CoV-2 variants in Ecuador.
New microbes and new infections 20220706
<h4>Background</h4>COVID-19 infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause mild symptoms to severe illness and death. Co-infections of SARS-CoV-2 with other respiratory viruses have been described. However, two SARS-CoV-2 lineage co-infection have been rarely reported.<h4>Methodology</h4>A genotyping analysis and two different types of whole genome sequencing were performed (Illumina MiniSeq and ONT MinION). When examining the phylogenetic analysis in ...[more]