The Association Between Bacille Calmette-Guerin Vaccination and Nontuberculous Mycobacterial Pulmonary Disease.

ABSTRACT: This study aimed to investigate the association between Bacille Calmette-Guérin (BCG) vaccination and nontuberculous mycobacterial pulmonary disease (NTM-PD). Patients in the prospective NTM-PD cohort were matched to healthy controls to measure the association between BCG and NTM-PD development. The clinical course of NTM-PD patients was also evaluated to investigate the association between BCG and NTM-PD progression. BCG scars were not associated with NTM-PD development (adjusted odds ratio [OR], 2.04; 95% confidence interval [CI], 0.96-4.34) or progression (adjusted OR, 1.61; 95% CI, 0.92-2.81). In conclusion, BCG vaccination was not associated with the development or progression of NTM-PD.

SUBMITTER: Kwak N 

PROVIDER: S-EPMC9259246 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature