Proportional-assist ventilation with load-adjustable gain factors for mechanical ventilation: a cost-utility analysis.

ABSTRACT:

Background

Mechanical ventilation is an important component of patient critical care, but it adds expense to an already high-cost setting. This study evaluates the cost-utility of 2 modes of ventilation: proportional-assist ventilation with load-adjustable gain factors (PAV+ mode) versus pressure-support ventilation (PSV).

Methods

We adapted a published Markov model to the Canadian hospital-payer perspective with a 1-year time horizon. The patient population modelled includes all patients receiving invasive mechanical ventilation who have completed the acute phase of ventilatory support and have entered the recovery phase. Clinical and cost inputs were informed by a structured literature review, with the comparative effectiveness of PAV+ mode estimated via pragmatic meta-ana

SUBMITTER: Saunders R 

PROVIDER: S-EPMC9259387 | biostudies-literature | 2022 Jan-Mar

REPOSITORIES: biostudies-literature