Associations between steady-state pattern electroretinography and estimated retinal ganglion cell count in glaucoma suspects.

ABSTRACT:

Purpose

To estimate retinal ganglion cell (RGC) count in glaucoma suspects (GS) and ascertain its relationships with steady-state pattern electroretinography (ssPERG) parameters.

Methods

In this prospective cross-sectional study, 22 subjects (44 eyes) were recruited at the Manhattan Eye, Ear, and Throat Hospital. Subjects underwent complete eye examinations, optical coherence tomography, standard automated perimetry, and ssPERG testing. Eyes were divided into two groups based upon clinical data: healthy subjects and GS. RGC count was estimated using the combined structure-function index.

Results

Estimated RGC count, average retinal nerve fiber layer thickness (ARNFLT), and average ganglion cell layer and inner plexiform layer thickness (GCIPLT) were reduced in GS eyes

SUBMITTER: Tirsi A 

PROVIDER: S-EPMC9259521 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature