Rickettsia helvetica infection is associated with microbiome modulation in Ixodes ricinus collected from humans in Serbia.

ABSTRACT: Rickettsia helvetica is an emerging pathogen of the Spotted Fever Group Rickettsia (SFGR) causing spotted fever diseases in various European countries. This tick-borne pathogen replicates in tick tissues such as the midgut and salivary gland, but its potential interactions with the vector microbiota is poorly characterized. The vector microbiome plays a pivotal role in tick-pathogen interactions, and some microbiota members facilitate or impede tick-borne pathogen infection. Manipulations of the tick microbiome have led to reduction in pathogen colonization in the tick vector. However, translating these findings into disease control applications requires a thorough characterization of vector microbiota response to different pathogens. In this study, we analyzed and compared the microbiota

SUBMITTER: Maitre A 

PROVIDER: S-EPMC9259644 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature