The association of lung function and pulmonary vasculature volume with cardiorespiratory fitness in the community.

ABSTRACT:

Background

Cardiorespiratory fitness is not limited by pulmonary mechanical reasons in the majority of adults. However, the degree to which lung function contributes to exercise response patterns among ostensibly healthy individuals remains unclear.

Methods

We examined 2314 Framingham Heart Study participants who underwent cardiopulmonary exercise testing (CPET) and pulmonary function testing. We investigated the association of forced expiratory volume in 1 s (FEV₁), forced vital capacity (FVC), FEV₁/FVC and diffusing capacity of the lung for carbon monoxide (D _LCO) with the primary outcome of peak oxygen uptake (V'_O2 ) along with other CPET parameters using multivariable linear regression. Finally, we inve

SUBMITTER: McNeill J 

PROVIDER: S-EPMC9259762 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature