Trends in Androgen Deprivation Use in Men With Intermediate-Risk Prostate Cancer Who Underwent Radiation Therapy.

ABSTRACT:

Purpose

Until 2018, National Cancer Comprehensive Network guidelines recommended androgen deprivation therapy (ADT) for all men with intermediate-risk prostate cancer who had undergone radiation therapy. Intermediate risk was stratified as favorable and unfavorable in 2018, and ADT recommendation was limited to men with unfavorable intermediate-risk prostate cancer. Data suggesting this stratification and treatment deintensification were first published in December 2013. This study characterizes US national trends for demographic, clinical, and socioeconomic factors associated with ADT use in men with intermediate-risk prostate cancer who have undergone definitive radiation therapy.

Methods and materials

This retrospective cohort study examined 108,185 men in the National Ca

SUBMITTER: Agrawal V 

PROVIDER: S-EPMC9260097 | biostudies-literature | 2022 Jul-Aug

REPOSITORIES: biostudies-literature