COMPERA 2.0: a refined four-stratum risk assessment model for pulmonary arterial hypertension.

ABSTRACT:

Background

Risk stratification plays an essential role in the management of patients with pulmonary arterial hypertension (PAH). The current European guidelines propose a three-stratum model to categorise risk as low, intermediate or high, based on the expected 1-year mortality. However, with this model, most patients are categorised as intermediate risk. We investigated a modified approach based on four risk categories, with intermediate risk subdivided into intermediate-low and intermediate-high risk.

Methods

We analysed data from the Comparative, Prospective Registry of Newly Initiated Therapies for Pulmonary Hypertension (COMPERA), a European pulmonary hypertension registry, and calculated risk at diagnosis and first follow-up based on World Health Organization functiona

SUBMITTER: Hoeper MM 

PROVIDER: S-EPMC9260123 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature