Recommendations for the use of propensity score methods in multiple sclerosis research.

ABSTRACT:

Background

With many disease-modifying therapies currently approved for the management of multiple sclerosis, there is a growing need to evaluate the comparative effectiveness and safety of those therapies from real-world data sources. Propensity score methods have recently gained popularity in multiple sclerosis research to generate real-world evidence. Recent evidence suggests, however, that the conduct and reporting of propensity score analyses are often suboptimal in multiple sclerosis studies.

Objectives

To provide practical guidance to clinicians and researchers on the use of propensity score methods within the context of multiple sclerosis research.

Methods

We summarize recommendations on the use of propensity score matching and weighting based on the current m

SUBMITTER: Simoneau G 

PROVIDER: S-EPMC9260471 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature