Foot Osteomyelitis Location and Rates of Primary or Secondary Major Amputations in Patients With Diabetes.

ABSTRACT:

Background

Diabetic foot osteomyelitis (DFO) often leads to amputations in the lower extremity. Data on the influence of the initial anatomical DFO localization on ultimate major amputation are limited.

Methods

In this retrospective analysis, 583 amputation episodes in 344 patients (78 females, 266 males) were analyzed. All received a form of amputation in combination with antibiotic therapy. A multivariate logistic regression analysis with the primary outcome "major amputation" defined as an amputation above the ankle joint was performed. The association of risk factors including location of DFO, coronary artery disease, peripheral artery disease, neuropathy, nephropathy, and Charcot neuro-osteoarthropathy was analyzed.

Results

Among 583 episodes, DFO was located in

SUBMITTER: Winkler E 

PROVIDER: S-EPMC9260474 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature