Neuroprotective strategies with circulatory arrest in open aortic surgery - A meta-analysis.

ABSTRACT:

Objective

Deep hypothermic circulatory arrest (DHCA) in aortic surgery is associated with morbidity and mortality despite evolving strategies. With the advent of antegrade cerebral perfusion (ACP), moderate hypothermic circulatory arrest (MHCA) was reported to have better outcomes than DHCA. There is no standardised guideline or consensus regarding the hypothermic strategies to be employed in open aortic surgery. Meta-analysis was performed comparing DHCA with MHCA + ACP in patients having aortic surgery.

Methods

A systematic review of the literature was undertaken. Any studies with DHCA versus MHCA + ACP in aortic surgeries were selected according to specific inclusion criteria and analysed to generate summative data. Statistical analysis was performed using STATS Direct. T

SUBMITTER: Manoly I 

PROVIDER: S-EPMC9260478 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature