Extended Focal Ablation of Localized Prostate Cancer With High-Frequency Irreversible Electroporation: A Nonrandomized Controlled Trial.

ABSTRACT:

Importance

Focal therapy of prostate cancer must balance the oncologic outcome and functional outcome. High-frequency irreversible electroporation (H-FIRE) can destroy cancer cells while selectively preserving surrounding nerves and blood vessels, but no clinical trials have been conducted, to our knowledge.

Objective

To evaluate the efficacy and safety of H-FIRE in the treatment of localized prostate cancer (PCa).

Design, setting, and participants

This was a single-group, objective performance criteria, nonrandomized controlled trial. Recruitment began on May 2, 2018, and ended March 27, 2019. The follow-up duration was 6 months. This was a multicenter trial conducted at 4 tertiary teaching hospitals in China. Patients with low or intermediate risk of biochemical rec

SUBMITTER: Wang H 

PROVIDER: S-EPMC9260646 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature