Preoperative Prediction of the Aggressiveness of Oral Tongue Squamous Cell Carcinoma with Quantitative Parameters from Dual-Energy Computed Tomography.

ABSTRACT:

Objectives

To determine whether quantitative parameters derived from dual-energy computed tomography (DECT) were predictive of the aggressiveness of oral tongue squamous cell carcinoma (OTSCC) including the pathologic stages, histologic differentiation, lymph node status, and perineural invasion (PNI).

Methods

Between August 2019 and March 2021, 93 patients (mean age, 54.6 ± 13.8 years; 66 men) with pathologically diagnosed OTSCC were enrolled in this prospective study. Preoperative DECT was performed and quantitative parameters (e.g., slope of the spectral Hounsfield unit curve [λ_Hu], normalized iodine concentration [nIC], normalized effective atomic number [nZ_eff], and normalized electron density [nRho]) were measured on arterial phase (AP) and venous

SUBMITTER: Yang X 

PROVIDER: S-EPMC9260668 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature