Enhanced Antioxidant Ability of PEG-Coated Ce_0.5Zr_0.5O₂-Based Nanofluids for Scavenging Hydroxyl Radicals.

ABSTRACT: The antioxidant therapy to preserve residual hearing is relatively recent, and the search for effective antioxidants is still ongoing. Though nanoceria has shown promising radical-scavenging capability, improving its antioxidant ability and the dispersion stability of its nanofluid, which is critical to the desired site, i.e., cochlea, still remains a major challenge. The objective of the present work is to study the radical-scavenging capability of poly(ethylene glycol) (PEG)-coated CeO₂ and Ce_0.5Zr_0.5O₂ nanoparticles in water and the biologically relevant fluid (PBS buffer). Nanoparticles in the size range of 4.0-9.0 nm are synthesized using the coprecipitation method and characterized using suitable techniques. The scavenging and dispersion st

SUBMITTER: Rai N 

PROVIDER: S-EPMC9260909 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature