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The value of repeat kidney biopsy during an atypical course of membranous nephropathy.


ABSTRACT:

Background

The clinical trajectory for patients with primary membranous nephropathy ranges widely from spontaneous remission to a rapid decline in kidney function. Etiologies for rapid progression with membranous nephropathy include concurrent bilateral renal vein thrombosis, malignant hypertension, and crescentic membranous nephropathy. Given the wide heterogeneity in prognosis, timing of immunosuppressive therapy is often challenging and centers around an individual patient's perceived risk for rapidly progressive disease.

Case presentation

Herein, we describe the clinical course of a young patient who initially developed a typical presentation of membranous nephropathy with consistent kidney biopsy findings. Given clinical stability, a six month observation period was und

SUBMITTER: Ahmed S 

PROVIDER: S-EPMC9260970 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature