Rubus idaeus extract improves symptoms in knee osteoarthritis patients: results from a phase II double-blind randomized controlled trial.

ABSTRACT:

Background

Osteoarthritis (OA) is the most frequent cause of disability in elderly people. In daily practice, the main objective of the physician is to reduce patient symptoms using treatments without adverse effects. However, the most prescribed treatment to manage OA symptoms remains nonsteroidal anti-inflammatory drugs which are associated with severe adverse effects. Therefore, we need a safe alternative to managing OA. One candidate is Rubus idaeus leaf extracts known to inhibit inflammatory responses.

Objective

This study aimed to evaluate the effects of a 12-weeks intervention with an ethanolic extract from Rubus idaeus leaf on symptoms of knee osteoarthritis.

Method

The study was a randomized, double-blind, placebo-controlled, monocentric trial of 198 particip

SUBMITTER: Henrotin Y 

PROVIDER: S-EPMC9261022 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature