The positive dimension of schizotypy is associated with a reduced attenuation and precision of self-generated touch.

ABSTRACT: The brain predicts the sensory consequences of our movements and uses these predictions to attenuate the perception of self-generated sensations. Accordingly, self-generated touch feels weaker than an externally generated touch of identical intensity. In schizophrenia, this somatosensory attenuation is substantially reduced, suggesting that patients with positive symptoms fail to accurately predict and process self-generated touch. If an impaired prediction underlies the positive symptoms of schizophrenia, then a similar impairment should exist in healthy nonclinical individuals with high positive schizotypal traits. One hundred healthy participants (53 female), assessed for schizotypal traits, underwent a well-established psychophysics force discrimination task to quantify how they percei

SUBMITTER: Asimakidou E 

PROVIDER: S-EPMC9261081 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature