Neural alterations of emotion processing in atypical trajectories of psychotic-like experiences.

ABSTRACT: The aim of this study was to investigate the neural bases of facial emotion processing before the onset of clinical psychotic symptoms in youth belonging to well-defined developmental trajectories of psychotic-like experiences (PLEs). A unique sample of 86 youths was recruited from a population-based sample of over 3800 adolescents who had been followed from 13 to 17 years of age. Three groups were identified based on validated developmental trajectories: a control trajectory with low and decreasing PLEs, and two atypical trajectories with moderate to elevated baseline PLEs that subsequently decreased or increased. All had functional magnetic resonance imaging data collected during a facial emotion processing task. Functional activation and connectivity data were analyzed for different con

SUBMITTER: Assaf R 

PROVIDER: S-EPMC9261083 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature