Validation of accelerometry as a digital phenotyping measure of negative symptoms in schizophrenia.

ABSTRACT: Negative symptoms are commonly assessed via clinical rating scales; however, these measures have several inherent limitations that impact validity and utility for their use in clinical trials. Objective digital phenotyping measures that overcome some of these limitations are now available. The current study evaluated the validity of accelerometry (ACL), a passive digital phenotyping method that involves collecting data on the presence, vigor, and variability of movement. Outpatients with schizophrenia (SZ: n = 50) and demographically matched healthy controls (CN: n = 70) had ACL continuously recorded from a smartphone and smartband for 6 days. Active digital phenotyping assessments, including surveys related to activity context, were also collected via 8 daily surveys throughout the 6 day

SUBMITTER: Strauss GP 

PROVIDER: S-EPMC9261099 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature