Maternal acetaminophen use and cognitive development at 4 years: the Ontario Birth Study.

ABSTRACT:

Background

Studies have suggested a link between prenatal maternal acetaminophen use and adverse developmental outcomes in children. However, there exists a knowledge gap regarding overall cognitive development and use of acetaminophen, especially concerning the timing of use in pregnancy. This study aimed to characterize the relationship between maternal acetaminophen use and cognitive development at 4 years.

Methods

This analysis included data collected throughout pregnancy and delivery from women in the Ontario Birth Study prospective cohort from 2013 to 2019 and from the NIH Toolbox Early Childhood Cognition battery administered to 4-year-old children between 2018 and 2021 (n = 436). The exposure was maternal acetaminophen use and the primary outcome was a cognition comp

SUBMITTER: Lye JM 

PROVIDER: S-EPMC9261144 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature