CT and ¹⁸F-FDG PET abnormalities in contacts with recent tuberculosis infections but negative chest X-ray.

ABSTRACT: Close contacts of individuals with pulmonary tuberculosis are at risk for tuberculosis infection and the development of active tuberculosis. In current contact investigations, immunologic tests (the tuberculin skin test and interferon-gamma release assay) and chest X-ray examinations are used to dichotomize contacts with Mycobacterium tuberculosis infections into those with active (X-ray abnormalities) versus latent tuberculosis (normal radiographs). This article is a critical review of computed tomographic (CT) and 18-fluorodeoxyglucose positron emission tomographic (PET) findings of incipient tuberculosis without X-ray abnormalities based on a systematic literature review of twenty-five publications. The CT and 18-fluorodeoxyglucose PET studies revealed minimal pauci-nodular infiltration

SUBMITTER: Yoon SH 

PROVIDER: S-EPMC9261169 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature