Longitudinal changes in auditory and reward systems following receptive music-based intervention in older adults.

ABSTRACT: Listening to pleasurable music is known to engage the brain's reward system. This has motivated many cognitive-behavioral interventions for healthy aging, but little is known about the effects of music-based intervention (MBI) on activity and connectivity of the brain's auditory and reward systems. Here we show preliminary evidence that brain network connectivity can change after receptive MBI in cognitively unimpaired older adults. Using a combination of whole-brain regression, seed-based connectivity analysis, and representational similarity analysis (RSA), we examined fMRI responses during music listening in older adults before and after an 8-week personalized MBI. Participants rated self-selected and researcher-selected musical excerpts on liking and familiarity. Parametric effects of

SUBMITTER: Quinci MA 

PROVIDER: S-EPMC9261172 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature