RNAseq of Osteoarthritic Synovial Tissues: Systematic Literary Review.

ABSTRACT: Osteoarthritis (OA) is one of the most common causes of disability in aged people, and it is defined as a degenerative arthropathy, characterized by the disruption in joint tissue. The synovium plays a vital role in maintaining the health of the joint by supplying the nutrients to the surrounding tissues and the lubrication for joint movement. While it is well known that all the joint tissues are communicating and working together to provide a functioning joint, most studies on OA have been focused on bone and cartilage but much less about synovium have been reported. The purpose of this review was to investigate the current literature focused on RNA sequencing (RNAseq) of osteoarthritic synovial tissues to further understand the dynamic transcriptome changes occurring in this pivotal join

SUBMITTER: Moore L 

PROVIDER: S-EPMC9261452 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature