Adverse effects on birth weight of parental illegal drug use during pregnancy and within two years before pregnancy.

ABSTRACT: This study investigates possible links between maternal illegal drug use during pregnancy and up to two years before pregnancy with birth weight (BW), and explores the potential role of paternal illegal drug use on low birth weight. A population-based retrospective cohort study was conducted that linked four national databases in Taiwan. A total of 1,698 subjects with a criminal record of schedule I or II illegal drug use within two years before pregnancy were enrolled as the drug-exposed group, and 16,980 matched subjects were enrolled as the unexposed group. Multivariate analysis of BW found a decrease of 108.63 g (95% CI: -172.29, -44.96), 79.67 g (95% CI: -116.91, -42.43), and 69.78 g (95% CI: -106.71, -32.84) in newborns whose mothers used illegal drugs only during pregnancy (period I

SUBMITTER: Lin CH 

PROVIDER: S-EPMC9261820 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature