Rapid determination of benzophenone derivatives in cereals using FaPEx coupled with ultra-high-performance liquid chromatography-tandem mass spectrometry.

ABSTRACT: A robust and sensitive analytical method was developed and validated for the simultaneous analysis of the levels of 10 benzophenone derivatives (BPs; BP, BP-1, BP-2, BP-3, BP-8, 2-hydroxybenzophenone [2-OHBP], 4-hydroxybenzophenone [4-OHBP], 4-methylbenzophenone [4-MBP], methyl-2-benzoylbenzoate [M2BB], and 4-benzoylbiphenyl [PBZ]) in 54 breakfast cereal samples. A fast pesticide extraction (FaPEx) technique coupled with isotope-labeled internal standards ultra-high-performance liquid chromatography-tandem mass spectrometry was employed. The developed method exhibited satisfactory linearity (R² > 0.998), high precision (intraday and interday relative standard deviations in the ranges of 1.4%-20.8% and 3.2%-23.9%, respectively), and a limit of detection ranging from 0.001 to 0.12

SUBMITTER: Huang YF 

PROVIDER: S-EPMC9261831 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature