Temporal Summation in Fibromyalgia Patients: Comparing Phasic and Tonic Paradigms.

ABSTRACT:

Introduction

Fibromyalgia (FM) is associated with dysfunctional pain modulation mechanisms, including central sensitization. Experimental pain measurements, such as temporal summation (TS), could serve as markers of central sensitization and have been previously studied in these patients, with conflicting results. Our objective in this study was to explore the relationships between two different protocols of TS (phasic and tonic) and test the associations between these measures and other clinical variables.

Materials and methods

In this cross-sectional analysis of a randomized clinical trial, patients were instructed to determine their pain-60 test temperature, then received one train of 15 repetitive heat stimuli and rated their pain after the 1st and 15th stimuli: TSPS-pha

SUBMITTER: Castelo-Branco L 

PROVIDER: S-EPMC9261961 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature