Pulmonary Microbial Composition in Sepsis-Induced Acute Respiratory Distress Syndrome.

ABSTRACT: Background: Acute respiratory distress syndrome (ARDS) is an unresolved challenge in the field of respiratory and critical care, and the changes in the lung microbiome during the development of ARDS and their clinical diagnostic value remain unclear. This study aimed to explore the role of the lung microbiome in disease progression in patients with sepsis-induced ARDS and potential therapeutic targets. Methods: Patients with ARDS were divided into two groups according to the initial site of infection, intrapulmonary infection (ARDSp, 111 cases) and extrapulmonary infection (ARDSexp, 45 cases), and a total of 28 patients with mild pulmonary infections were enrolled as the control group. In this study, we sequenced the DNA in the bronchoalveolar lavage fluid collected from pati

SUBMITTER: Zhang P 

PROVIDER: S-EPMC9262094 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature