Post-remission outcomes in AML patients with high hyperleukocytosis and inaugural life-threatening complications.

ABSTRACT:

Introduction

Patients with hyperleukocytic (HL) acute myeloid leukemia (AML) are at higher risk of early death. Initial management of these patients is challenging, not fully codified and heterogenous. Retrospective studies showed that several symptomatic measures might decrease early death rate but long-term data are scarce. We aimed to analyze whether the therapeutic measures carried out urgently at diagnosis may influence the outcome among HL AML patients having achieved who survived inaugural complications.

Methods

We retrospectively reviewed all medical charts from patients admitted to Saint-Louis Hospital between January, 1st 1997 and December, 31st 2018 with newly diagnosed AML and white blood cell (WBC) count above 50x109/L. Outcome measures were cumulative incidence

SUBMITTER: Fodil S 

PROVIDER: S-EPMC9262217 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature