Seaweed and Iodine Intakes and SLC5A5 rs77277498 in Relation to Thyroid Cancer.

ABSTRACT:

Backgruound

This study aims to elucidate the associations among dietary seaweed (gim and miyeok/dashima) and iodine intakes, the rs77277498 polymorphism of the SLC5A5 gene codifying the sodium/iodine symporter, and thyroid cancer risk in a Korean population.

Methods

We conducted a case-control study of 117 thyroid cancer cases and 173 controls who participated in the Cancer Screenee Cohort between 2002 and 2014 at the National Cancer Center, Korea. The amount of seaweed and iodine consumption (g/day) was estimated using the residual energy adjustment method. We calculated odds ratios (ORs) and their 95% confidence intervals (CIs) using a multivariable logistic regression model for the separate and combined effect of dietary iodine-based intake and SLC5A5 polymorphism (rs7727

SUBMITTER: Hoang T 

PROVIDER: S-EPMC9262681 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature