Clinical Outcomes of Repeated Radioactive Iodine Therapy for Graves' Disease.

ABSTRACT:

Backgruound

Radioactive iodine (RAI) therapy is a successful therapeutic modality for Graves' disease. However, RAI therapy can fail, and RAI therapy after antithyroid drugs (ATDs) has a lower remission rate. Therefore, many patients require repeated RAI therapy. This study investigated the clinical outcomes of repeated RAI therapy for Graves' disease.

Methods

Patients who underwent RAI therapy as second-line therapy after failure of ATD treatment between 2001 and 2015 were reviewed. Remission was defined as hypothyroid or euthyroid status without ATD, and with or without levothyroxine at 12 months after RAI therapy.

Results

The 1-year remission rate after 2nd RAI therapy (66%, 152/230) is significantly higher than that after 1st RAI therapy (48%, 393/815) or long-ter

SUBMITTER: Kim MJ 

PROVIDER: S-EPMC9262691 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature