Extra-Glycemic Effects of Anti-Diabetic Medications: Two Birds with One Stone?

ABSTRACT: The world is suffering from a rapid increase in the number of people with diabetes due to the increased prevalence of obesity and lengthened life span. Since the development of insulin thanks to the efforts of Prof. Banting and Dr. Best in 1922, for which they won the Nobel Prize, remarkable developments in anti-diabetic medications have dramatically lengthened the lifespan of patients with diabetes. However, the control rate of hyperglycemia in patients with diabetes remains unsatisfactory, since glycemic control requires both medication and lifestyle modifications to slow the deterioration of pancreatic beta-cell function and prevent diabetic complications. From the initial "triumvirate" to the "ominous octet," and now the "egregious eleven," the number of organs recognized as being invo

SUBMITTER: Rhee EJ 

PROVIDER: S-EPMC9262696 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature