Elevated thyroid hormones caused by high concentrate diets participate in hepatic metabolic disorders in dairy cows.

ABSTRACT:

Objective

High concentrate diets are widely used to satisfy high-yielding dairy cows; however, long-term feeding of high concentrate diets can cause subacute ruminal acidosis (SARA). The endocrine disturbance is one of the important reasons for metabolic disorders caused by SARA. However, there is no current report about thyroid hormones involved in liver metabolic disorders induced by a high concentrate diet.

Methods

In this study, 12 mid-lactating dairy cows were randomly assigned to HC (high concentrate) group (60% concentrate of dry matter, n = 6) and LC (low concentrate) group (40% concentrate of dry matter, n = 6). All cows were slaughtered on the 21st day, and the samples of blood and liver were collected to analyze the blood biochemistry, histological changes, thyroi

SUBMITTER: Chen Q 

PROVIDER: S-EPMC9262717 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature