Three new experimental models of anterior urethral stricture in rabbits.

ABSTRACT:

Background

This study describes and compares three surgical procedures for the construction of urethral stricture (US) models in rabbits.

Methods

Forty adult male rabbits were allocated to four groups: 36 rabbits were randomly assigned to three experimental groups, while the remaining 4 were assigned to a sham group. The penis was separated from the rectum. Then along the ventral midline, a longitudinal penile skin incision was made while ensuring that the urethral mucosa was intact and the muscular layer was not completely incised. In group 1 (n=12), ventral semi-circumferential mucosa electrocoagulation of a 1-cm length of the anterior urethra was performed until ulceration occurred. In group 2 (n=12), the ventral urethral mucosa was incised, and electrocoagulation of the

SUBMITTER: Yao HJ 

PROVIDER: S-EPMC9262740 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature