Coronary Artery Calcium for Risk Stratification of Sudden Cardiac Death: The Coronary Artery Calcium Consortium.

ABSTRACT:

Background

Coronary artery calcium (CAC) is a marker of plaque burden. Whether CAC improves risk stratification for incident sudden cardiac death (SCD) beyond atherosclerotic cardiovascular disease (ASCVD) risk factors is unknown.

Objectives

SCD is a common initial manifestation of coronary heart disease (CHD); however, SCD risk prediction remains elusive.

Methods

The authors studied 66,636 primary prevention patients from the CAC Consortium. Multivariable competing risks regression and C-statistics were used to assess the association between CAC and SCD, adjusting for demographics and traditional risk factors.

Results

The mean age was 54.4 years, 33% were women, 11% were of non-White ethnicity, and 55% had CAC >0. A total of 211 SCD events (0.3%) were observed

SUBMITTER: Razavi AC 

PROVIDER: S-EPMC9262828 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature