An international Delphi exercise to identify items of importance for measuring response to treatment in ANCA-associated vasculitis.

ABSTRACT:

Objective

ANCA-associated vasculitis (AAV) is characterized by fluctuating levels of disease activity, but no formal criteria exist to measure response to treatment. This Delphi exercise aimed to reach consensus about which measures are considered by patients and physicians to be most important when assessing response to treatment in clinical trials of AAV.

Methods

An international 3-round online Delphi exercise was conducted. Survey participants included patients with AAV and physicians with expertise in AAV. Survey participants were asked to rate (on a scale of 1-9) the importance of each item when assessing response to treatment in AAV. Items scored 7-9 by ≥70% participants were considered highly important.

Results

89 patients and 176 physicians completed three rou

SUBMITTER: Quinn KA 

PROVIDER: S-EPMC9262834 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature