Meta-Analysis of Structural and Functional Brain Abnormalities in Cocaine Addiction.

ABSTRACT:

Background

Previous voxel-based morphometric (VBM) and functional magnetic resonance imaging (fMRI) studies have shown changes in brain structure and function in cocaine addiction (CD) patients compared to healthy controls (HC). However, the results of these studies are poorly reproducible, and it is unclear whether there are common and specific neuroimaging changes. This meta-analysis study aimed to identify structural, functional, and multimodal abnormalities in CD patients.

Methods

The PubMed database was searched for VBM and task-state fMRI studies performed in CD patients between January 1, 2010, and December 31, 2021, using the SEED-BASE d MAP software package to perform two independent meta-groups of functional neural activation and gray matter volume, respectively. A

SUBMITTER: Dang J 

PROVIDER: S-EPMC9263080 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature