Neonatal sepsis-causing bacterial pathogens and outcome of trends of their antimicrobial susceptibility a 20-year period at a neonatal intensive care unit.

ABSTRACT:

Background

Due to increases in the number of infants born with younger gestational age (GA) and lower birth weight, the incidence of neonatal sepsis is increasing.

Purpose

We investigated the changes in the prevalence of bacterial pathogens, their antimicrobial susceptibility, and sepsis-related mortality during 20 years at a neonatal intensive care unit.

Methods

The study period was divided into two 10-year phases (1998-2007 vs. 2008-2017). Medical records were reviewed to gather data on demographics, causative microbial pathogens, incidence of multidrug-resistant organisms, antimicrobial susceptibility, and rates of sepsis-related mortality.

Results

In both study phases, the most common pathogens for neonatal sepsis were coagulase-negative Staphylococcus (CoN

SUBMITTER: Song WS 

PROVIDER: S-EPMC9263424 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature