Bacterial coinfection and antimicrobial use among patients with COVID-19 infection in a referral center in the Philippines: A retrospective cohort study.

ABSTRACT:

Objective

This study aimed to describe community-acquired bacterial coinfection (CAI) and antimicrobial use among COVID-19 patients.

Methods

Electronic records were retrospectively reviewed, and clinical data, laboratory data, antibiotic use, and outcomes of patients with and without CAI were compared.

Results

Of 1116 patients, 55.1% received antibiotics within 48 hours, but only 66 (5.9%) had documented CAI, mainly respiratory (40/66, 60.6%). Patients with CAI were more likely to present with myalgia (p = 0.02), nausea/vomiting (p = 0.014), altered sensorium (p = 0.007), have a qSOFA ≥ 2 (p = 0.016), or require vasopressor support (p < 0.0001). Patients with CAI also had higher median WBC count (10 vs 7.6 cells/mm³), and

SUBMITTER: Abad CL 

PROVIDER: S-EPMC9263707 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature