Polymeric nanocarriers: A promising tool for early diagnosis and efficient treatment of colorectal cancer.

ABSTRACT:

Background

Colorectal cancer (CRC) is the third most prevalent type of cancer for incidence and second for mortality worldwide. Late diagnosis and inconvenient and expensive current diagnostic tools largely contribute to the progress of the disease. The use of chemotherapy in the management of CRC significantly reduces tumor growth, metastasis, and morbidity rates. However, poor solubility, low cellular uptake, nonspecific distribution, multiple drug resistance and unwanted adverse effects are still among the major drawbacks of chemotherapy that limit its clinical significance in the treatment of CRC. Owing to their remarkable advantages over conventional therapies, the use of nanotechnology-based delivery systems especially polymeric nanocarriers (PNCs) has revolutionized many fie

SUBMITTER: Haider M 

PROVIDER: S-EPMC9263757 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature