Diagnostic delay in IPF impacts progression-free survival, quality of life and hospitalisation rates.

ABSTRACT:

Background

The diagnosis of idiopathic pulmonary fibrosis (IPF) is often delayed up to several years. The objective of this study was to assess the impact of the diagnostic delay on progression-free survival, quality of life and hospitalisation rates.

Methods

A total of 264 incident patients with IPF were included immediately after their diagnosis and followed for up to 5 years, with regular collection of clinical data, quality-of-life questionnaires and assessment of disease progression. Hospitalisation data were extracted from electronic patient records. Analyses were performed on the entire cohort and strata according to forced vital capacity (FVC) at diagnosis.

Results

A long diagnostic delay (>1 year) was associated with worse progression-free survival compared w

SUBMITTER: Hoyer N 

PROVIDER: S-EPMC9263910 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature