KDELR1 Is an Independent Prognostic Predictor and Correlates With Immunity in Glioma.

ABSTRACT:

Background

Gliomas are the most malignant central nervous system tumors. With the development of sequencing technology, more potential biomarkers related to the treatment, prognosis, and molecular classification of glioma have been identified. Here, we intend to investigate the potential biological function and clinical value of a new biomarker in glioma.

Methods

KDELR1 expression data and the corresponding clinical information were downloaded from public databases and then preprocessed using R language. Correlation, Kaplan-Meier survival, and Cox regression analyses were performed to explore the clinical significance of KDELR1 in glioma patients. Furthermore, the immune infiltration and microenvironment parameters were evaluated via TIMER and CIBERSORT. Immunohistoch

SUBMITTER: Yuan Y 

PROVIDER: S-EPMC9263977 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature