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ABSTRACT: Background and objective
The prevalence of hypertrophic cardiomyopathy (HCM) is estimated to be 1 in 200 to 500 individuals, with systolic anterior motion (SAM) of the mitral valve (MV) and left ventricular outflow tract (LVOT) obstruction present in 60% to 70%. In this narrative review, we aim to elucidate the pathophysiology of SAM-septal contact and LVOT obstruction in HCM by presenting a detailed review on the anatomy of the MV apparatus in HCM, examining the various existing theories pertaining to the SAM phenomenon as supported by cardiac imaging, and providing a critical assessment of management strategies for SAM in HCM.Methods
A literature review was performed using PubMed, EMBASE, Ovid, and the Cochrane Library, of all scientific articles published through Decembe
SUBMITTER: Guigui SA
PROVIDER: S-EPMC9264047 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature