Association of Allostatic Load and All Cancer Risk in the SWAN Cohort.

ABSTRACT: Elevated chronic stress is thought to increase cancer risk, though the results so far have been inconsistent. In this study, we assessed the relationship between allostatic load (AL), a biological indicator of chronic stress, and overall cancer risk in 3015 women who participated in the Study of Women's Health Across the Nation (SWAN). Based on the distribution of AL, the study population was categorized into four groups, from the lowest (1st category) to the highest AL group (4th category). At baseline, African American and Hispanic women were more likely to be in the higher AL categories than White women (p < 0.001). In addition, women who smoked regularly, drank alcohol regularly, had no leisure physical activity, and had restless sleep were also more likely to be in the highe

SUBMITTER: Shen J 

PROVIDER: S-EPMC9264860 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature