Mortality and Major Cardiovascular Events among Patients with Multiple Myeloma: Analysis from a Nationwide French Medical Information Database.

ABSTRACT:

Background

No robust data assesses the risk of all-cause death and cardiovascular (CV) events in multiple myeloma (MM) patients.

Patients and methods

From 1 January to 31 December 2013, 3,381,472 adults were hospitalised (for any reason) in French hospitals. We identified 15,774 patients diagnosed with known MM at baseline. The outcome analysis (all-cause death, CV death, myocardial infarction (MI), ischaemic stroke, or hospitalization for bleedings) was performed with follow-ups starting at the time of the last event. For each MM patient, a propensity score-matched patient without MM was selected.

Results

The mean follow-up in the propensity-score-matched population was 3.7 ± 2.3 years. Matched patients with MM had a higher risk of all-death (yearly rate 20.02 vs. 11

SUBMITTER: Cottin Y 

PROVIDER: S-EPMC9264957 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature