Radiotherapy in the Management of Gastrointestinal Stromal Tumors: A Systematic Review.

ABSTRACT: Gastrointestinal stromal tumors (GISTs) are considered insensitive to radiotherapy. However, a growing number of case reports and case series have shown that some lesions treated by radiotherapy achieved an objective response. The aim of the study was to perform a systematic review of all reported cases, case series, and clinical studies of GISTs treated with radiotherapy to reevaluate the role of radiotherapy in GISTs. A systematic search of the English-written literature was conducted using PubMed, Web of Science, and Embase databases. Overall, 41 articles describing 112 patients were retrieved. The included articles were of low to moderate quality. Bone was the most common site treated by radiotherapy, followed by the abdomen. In order to exclude the influence of effective tyrosine kina

SUBMITTER: Zhang H 

PROVIDER: S-EPMC9265110 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature