Prediction Models and Decision Aids for Women with Ductal Carcinoma In Situ: A Systematic Literature Review.

ABSTRACT: Even though Ductal Carcinoma in Situ (DCIS) can potentially be an invasive breast cancer (IBC) precursor, most DCIS lesions never will progress to IBC if left untreated. Because we cannot predict yet which DCIS lesions will and which will not progress, almost all women with DCIS are treated by breast-conserving surgery +/- radiotherapy, or even mastectomy. As a consequence, many women with non-progressive DCIS carry the burden of intensive treatment without any benefit. Multiple decision support tools have been developed to optimize DCIS management, aiming to find the balance between over- and undertreatment. In this systematic review, we evaluated the quality and added value of such tools. A systematic literature search was performed in Medline(ovid), Embase(ovid), Scopus and TRIP. Follow

SUBMITTER: Schmitz RSJM 

PROVIDER: S-EPMC9265509 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature