Left atrial volume index predicts response to cardiac resynchronisation therapy: a systematic review and meta-analysis.

ABSTRACT:

Introduction

In responders, cardiac resynchronisation therapy (CRT) results in improved left ventricular (LV) function and reduced atrial arrhythmia. The aim of this meta-analysis was to assess the potential relationship between the left atrium (LA) volume and CRT response.

Material and methods

We systematically searched all electronic databases up to August 2018 in order to select clinical trials and observational studies that assessed the predictive value of LA volume index (LAVI) of CRT response. Left ventricular end-systolic volume (LVESV) reduction ≥ 15 ml and/or LV ejection fraction (EF) increase ≥ 10% were the documented criteria for positive CRT response.

Results

A total of 2191 patients recruited in 10 studies with mean follow-up duration of 10.5 months were

SUBMITTER: Bytyci I 

PROVIDER: S-EPMC9266875 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature