Ontology highlight
ABSTRACT:
SUBMITTER: Khodadust F
PROVIDER: S-EPMC9267012 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature
Khodadust Fatemeh F Ezdoglian Aiarpi A Steinz Maarten M MM van Beijnum Judy R JR Zwezerijnen Gerben J C GJC Jansen Gerrit G Tas Sander W SW van der Laken Conny J CJ
International journal of molecular sciences 20220625 13
Extensive angiogenesis is a characteristic feature in the synovial tissue of rheumatoid arthritis (RA) from a very early stage of the disease onward and constitutes a crucial event for the development of the proliferative synovium. This process is markedly intensified in patients with prolonged disease duration, high disease activity, disease severity, and significant inflammatory cell infiltration. Angiogenesis is therefore an interesting target for the development of new therapeutic approaches ...[more]