The effect of Helicobacter pylori eradication on C-reactive protein: results from a meta-analysis.

ABSTRACT:

Introduction

Helicobacter pylori is a bacterium that causes chronic gastroduodenal infection and affects various systemic diseases. An increase in the blood level of C-reactive protein (CRP; a systemic inflammatory marker), at a low-grade chronic inflammation level, is observed in cases of infection. However, the effect of H. pylori eradication on CRP remains undetermined. Therefore, we aimed to evaluate the circulating CRP levels in eradicated patients through a meta-analysis.

Material and methods

The PubMed database was searched from its inception to June 2020. Studies that described the CRP levels following H. pylori eradication were collected. A random-effects meta-analysis was then performed using inverse variance with standardized mean difference.<

SUBMITTER: Watanabe J 

PROVIDER: S-EPMC9267031 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature